摘要
子宫肌瘤(uterine leiomyoma, UL)是女性最常见的生殖系统良性肿瘤,约50% UL患者出现临床症状,严重影响生活质量,且尚无明确的实验室检查作为辅助检查手段。炎症反应在子宫平滑肌瘤发病机制中发挥重要作用。血小板–淋巴细胞比值、中性粒细胞–淋巴细胞比值、淋巴细胞–单核细胞比值和系统免疫炎症指数是炎症反应的综合反射,很容易从完整的血细胞计数中测量得出,也是临床可以使用的新兴炎症标志物,同时可作为多种疾病的生物标志物。因此,探讨PLR、NLR、LMR和SII在子宫肌瘤发生发展中的作用,可以更好地指导临床工作,对子宫肌瘤进行有效的一级和二级预防,延缓疾病的发展。
Uterine leiomyoma (UL) is the most common benign tumour of the reproductive system in women. Approximately 50% of patients with UL present with clinical symptoms that severely affect quality of life, and there are no definitive laboratory tests available as an adjunct. The inflammatory re-sponse plays an important role in the pathogenesis of uterine smooth muscle tumours. The plate-let-lymphocyte ratio, neutrophil-lymphocyte ratio, lymphocyte-monocyte ratio and systemic im-mune inflammatory index are comprehensive reflections of the inflammatory response that can be easily measured from a complete blood count and are emerging inflammatory markers that can be used clinically, as well as being used as biomarkers for a variety of diseases. Therefore, exploring the role of PLR, NLR, LMR and SII in the development of uterine fibroids can better guide clinical ef-forts to provide effective primary and secondary prevention of fibroids and delay the progression of the disease.
出处
《临床医学进展》
2023年第2期2778-2783,共6页
Advances in Clinical Medicine
