慢性创面的病因及发病机制的研究进展

Advances in the Study of the Etiology and Pathogenesis of Chronic Wounds

慢性创面作为一类长期消耗性的皮肤系统疾病,是当前创面修复相关领域亟待解决的难题,给患者个人、社会带来了的沉重负担,该病的病因及发病机制复杂,涉及多方面因素,阐明其病因及发病机制有助于深入揭示慢性创面的致病机制并探究有效治疗靶点。本文就近年来慢性创面的病因及发病机制相关的研究进展进行综述,旨在为其分子机制及新的治疗靶点提供理论支持。

Chronic wound, a long-term wasting disease of the skin system, is an urgent problem in wounds re-pair, which poses a heavy burden to patients and society. The aetiology and pathogenesis of this disease are complex and multifaceted, and their elucidation can help to shed light on the patho-genesis of chronic wounds and explore effective therapeutic targets. In this paper, we review the recent research progress on the etiology and pathogenesis of chronic wounds to provide theoretical support for the molecular mechanisms and new therapeutic targets.