COPD与肥胖的相互关系研究进展

Research Progress on the Relationship between COPD and Obesity

慢性阻塞性肺疾病(COPD)是一种严重危害人类健康的常见多发疾病,常与多种疾病合并发生。近年来获越来越多的证据表明慢性阻塞性疾病患者常常合并高脂血症、肥胖等脂质代谢紊乱,虽然肥胖悖论的提出预示了新的诊疗方向,但其机制仍然未知。积极寻找可靠的指标,能早期发现、干预病情,评估疾病严重程度、病情进展,指导临床治疗。

Chronic obstructive pulmonary disease (COPD) is a common multiple disease that seriously en-dangers human health and often occurs in combination with a variety of diseases. In recent years, more and more evidence has shown that patients with chronic obstructive disease are often com-plicated with lipid metabolism disorders such as hyperlipidemia and obesity. Although the obesity paradox indicates a new direction of diagnosis and treatment, its mechanism is still unknown. Ac-tively looking for reliable indicators can detect and intervene the disease early, assess the severity and progression of the disease, and guide clinical treatment.