继发性甲状旁腺功能亢进症治疗进展

Progress in the Treatment of Secondary Hy-perparathyroidism

继发性甲状旁腺功能亢进(secondary hyperparathyroidism, SHPT)是慢性肾脏病(CKD)病人常见的严重并发症之一。甲状旁腺通过分泌甲状旁腺激素调节血钙水平来维持内分泌稳态。然而,SHPT会导致全身多个器官和系统的结构发生改变,这不仅会降低患者的生活质量,还会影响死亡率。因此对SHPT患者有效治疗及规范管理显得尤为重要,我们对SHPT的治疗做一综述,并且将重点叙述微创治疗进展。

Secondary hyperparathyroidism (SHPT) is one of the common and serious complications in patients with chronic kidney disease (CKD). Parathyroid gland maintains endocrine homeostasis by secret-ing parathyroid hormone to regulate the level of blood calcium. However, SHPT can lead to struc-tural changes in multiple organs and systems throughout the body, which will not only reduce the quality of life of patients, but also affect mortality. Therefore, the effective treatment and standard-ized management of patients with SHPT are particularly important. We review the treatment of SHPT, and will focus on the progress of minimally invasive treatment.