难治性抑郁症治疗方法的研究进展

Advances in the Treatment of Treatment-Resistant Depression

抑郁症是精神科疾病较为常见的心境障碍,核心症状是显著持久的情绪低落、兴趣减退等。具有病情严重、病程长、反复治疗效果差、患者社会功能恢复不良等特点,即便是接受规范化治疗的抑郁症患者,大约仍有30%成为难治性抑郁症患者。本文系统地阐述了难治性抑郁症各种治疗方法联合用药情况的现状,旨在探讨目前我国的抗抑郁药物应用现状,为合理选用治疗方案提供新的依据。

Depression is a common mood disorder in psychiatric diseases. The core symptoms are significant and lasting depression, loss of interest, etc. It has the characteristics of severe disease, long course of disease, poor effect of repeated treatment, and poor recovery of social function. Even with stand-ardized treatment, about 30% of patients with depression become treatment-resistant depression. This article systematically describes the current situation of the combination of various treatment methods for treatment-resistant depression, in order to explore the current situation of the appli-cation of antidepressant drugs in China, and provide a new basis for the rational selection of treat-ment programs.