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YBX1在组织器官纤维化中作用的研究进展

Research Progress on the Role of YBX1 in Tissue and Organ Fibrosis
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摘要 YBX1作为多功能结合蛋白,参与多种细胞过程,通过TGF-β通路、炎性因子、介导上皮间质转化、调节胶原蛋白的表达等多种机制,发挥致纤维化作用,YBX1有可能成为治疗纤维化的新靶点。 As a multifunctional binding protein, YBX1 is involved in a variety of cellular processes. It plays a fibrogenic role through TGF-β pathway, inflammatory factors, mediating epithelial interstitial transformation, regulating collagen expression and other mechanisms. YBX1 may become a new target for the treatment of fibrosis.
作者 李德莲 苏晓灵
机构地区 青海大学研究生院 青海省人民医院心血管内科
出处 《临床医学进展》 2023年第3期4136-4140,共5页 Advances in Clinical Medicine
关键词 Y盒结合蛋白1 纤维化 MICRORNA
分类号 R73 [医药卫生—肿瘤]
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临床医学进展
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