良性前列腺增生与下尿路症状

Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms

良性前列腺增生(Benign Prostatic Hyperplasia, BPH)是影响男性的最常见的疾病之一。BPH可导致患者的许多症状,通常称为下尿路症状(Lower Urinary Tract Symptoms, LUTS)。一些危险因素增加,如代谢疾病和肥胖,导致BPH发病率增加。在过去几十年中,发病率的增加带来了多种治疗方式。目前的治疗方法首先可分为内科或外科干预。目前来说,经尿道前列腺切除术(TURP)仍然是主要的治疗方式之一。但是,如果有另外更好的选择,许多患者会选择避免手术。药物治疗是一种有效的替代方法,然而,新的研究表明,药物治疗可能会有比以前认识到的更多的副作用。一些微创手术治疗(MIST)已经出现,提供了有效和持久的结果,同时在很大程度上使男性免受更具侵入性的手术所带来的副作用。BPH伴LUTS的治疗有一系列药物、程序和手术选择,本文主要叙述目前良性前列腺增生(BPH)患者下尿路症状(LUTS)的相关治疗方法以及未来发展方向。

Benign prostatic hyperplasia (BPH) is one of the most common diseases affecting men. BPH can cause many symptoms of patients, commonly referred to as lower urinary tract symptoms (LUTS). Some risk factors, such as metabolic diseases and obesity, increase the incidence rate of BPH. In the past decades, the increase in incidence rate has led to a variety of treatments. The current treat-ment methods can be divided into medical or surgical intervention. At present, transurethral pros-tatectomy (TURP) is still one of the main treatment methods. However, if there is another better choice, many patients will choose to avoid surgery. Drug treatment is an effective alternative. How-ever, new research shows that drug treatment may have more side effects than previously recog-nized. Some minimally invasive surgical treatments (MIST) have emerged, providing effective and lasting results, while largely protecting men from the side effects of more invasive surgery. There are a series of drugs, procedures and surgical options for the treatment of BPH with LUTS. This arti-cle mainly describes the current treatment methods and future development direction of lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH).