希氏束起搏研究进展

Research Progress of His Bundle Pacing

希氏束起搏(His bundle pacing, HBP)是通过将起搏电极植入希氏束而实现的一种生理性起搏技术。它通过天然传导系统激动心室,可避免起搏器诱发的心肌病等并发症,是一种安全有效的起搏替代方式。HBP不仅适用于各种原因导致的心动过缓,还能实现心脏再同步及作为心力衰竭患者的替代疗法。现有数据表明,HBP在维持或恢复心室同步性方面具有明显优势。此外,与传统右心室起搏相比,HBP的心房颤动发生率降低。在需要高百分比起搏时,其临床益处尤其显著。近年来HBP的研究发展迅速,本文对国内外关于HBP的最新研究成果进行综述,以便掌握其最新的前沿动态。

His bundle pacing (HBP) is a physiological pacing achieved by implanting pacing electrodes into his bundle. It stimulates the ventricle through the natural conduction system, which can avoid compli-cations such as cardiomyopathy induced by the pacemaker, and is a safe and effective alternative to pacing. HBP is not only suitable for bradycardia caused by various reasons, but also can realize car-diac resynchronization and serve as an alternative therapy for patients with heart failure. Available data indicate that HBP has obvious advantages in maintaining or restoring ventricular synchroniza-tion. In addition, compared with conventional right ventricular pacing, the incidence of atrial fibril-lation in HBP decreased. The clinical benefits are particularly significant when a high percentage of pacing is required. In recent years, the research on HBP has developed rapidly. This paper summa-rizes the latest research results of HBP at home and abroad in order to grasp its latest frontier trends.