慢性心力衰竭心肌重塑的中医研究进展

Advances in Chinese Medicine Research on Myocardial Remodelling in Chronic Heart Failure

心力衰竭(heart failure, HF)是目前全世界的常见疾病,心肌重构是心衰发生发展的重要机制,逆转心肌重构是治疗心衰的重要途径,可以表现为心肌纤维增多与线粒体的增大增多,现代医学研究发现中医在逆转心肌重塑方面有显著疗效,且研究已取得一定的进展,可以有效逆转心肌重构进而治疗心衰。文章从单味中药、中药复方、中药制剂等方面介绍中医药逆转心肌重塑的研究成果,为日后心衰诊疗提供参考依据。

Heart failure (HF) is now a common disease worldwide, myocardial remodelling is an important mechanism in the development of heart failure, and reversing myocardial remodelling is an im-portant way to treat heart failure, which can be manifested as an increase in myocardial fibres and an increase in the size of mitochondria, modern medical research has found that Chinese medicine has significant efficacy in reversing myocardial remodelling, and research has made some progress, in effectively reversing myocardial remodelling and thus treating heart failure. This article intro-duces the research results of TCM in reversing myocardial remodelling from single herbs, herbal compounds and herbal preparations, which will provide a reference basis for the future treatment of heart failure.