细菌性脑膜炎对儿童认知行为的影响

Effects of Bacterial Meningitis on the Cognitive Behavior of Children

细菌性脑膜炎是由多种病原菌感染引起的软脑膜和蛛网膜的化脓性炎症,是儿童常见的中枢神经系统感染性疾病,导致高死亡率。高达30%的幸存者有某种类型的神经或神经行为后遗症,其中认知障碍、行为障碍、心理问题等不典型后遗症是被严重低估的,并且严重影响生活质量。本文总结了现有的证据,以更好地了解细菌性脑膜炎患儿的认知、行为发育障碍及情绪心理问题等不典型后遗症的表现,提高大众对幸存者不典型后遗症的关注及重视,为制定新的随访管理指南提供帮助。

Bacterial meningitis is a suppurative inflammation of the pia meninges and arachnoid membranes caused by a variety of pathogenic bacteria. It is a common infectious disease of the central nervous system in children, leading to a high mortality rate. Up to 30% of survivors have some type of neu-rological or neurobehavioral sequelae, among which atypical sequelae such as cognitive impair-ment, behavioral disorder and psychological problems are grossly underestimated and seriously affect quality of life. This paper summarizes the existing evidence, so as to better understand the manifestations of atypical sequelae of children with bacterial meningitis, such as cognitive and be-havioral developmental disorders and psychological problems, raise the public’s attention to atypi-cal sequelae of survivors, and provide help for the development of new guidelines for follow-up management.