肺炎链球菌相关性迁延性细菌性支气管炎的研究现状

Current Situation of Research on Protracted Bacterial Bronchitis Associated with Streptococcus pneumoniae

肺炎链球菌是引起迁延性细菌性支气管炎(protracted bacterial bronchitis, PBB)的常见病原菌。目前国内外对其导致的侵袭性疾病及肺炎链球菌肺炎的关注度较高,并展开了广泛的研究。但对其引起的儿童慢性化脓性呼吸疾病如PBB的认识尚不足。本文就儿童肺炎链球菌相关性迁延性细菌性支气管炎的流行病学、发病机制、治疗及预后做一总结,提高临床医生对此病的认识。

Streptococcus pneumoniae is a common pathogen causing protracted bacterial bronchitis (PBB). Currently, invasive pneumococcal disease and Streptococcus pneumoniae pneumonia have attracted more attention, and extensive studies have been carried out. However, the understanding of chronic respiratory diseases such as PBB is still insufficient. This article summarizes the epidemiology, pathogenesis, treatment, and prognosis of protracted bacterial bronchitis associated with Strepto-coccus pneumoniae in children, to improve clinicians’ understanding of this disease.