幽门螺杆菌感染与皮肤疾病相关性的研究进展

Advances in the Association between Helicobacter pylori Infection and Skin Disorders

幽门螺杆菌是一种革兰阴性菌,感染世界上约50%的人群,其常定植于胃黏膜中,与胃肠溃疡、慢性胃炎、胃癌等胃肠道疾病联系紧密。近年来研究发现,幽门螺杆菌感染还与许多皮肤病变相关,包括但不限于玫瑰痤疮、慢性荨麻疹、复发性阿弗他溃疡、过敏性紫癜、免疫性血小板减少性紫癜等疾病。本文就幽门螺杆菌感染与皮肤疾病的研究进行综述,为临床决策提供帮助。

Helicobacter pylori are a gram-negative bacterium that infects nearly 50% of the world’s population. It colonizes the gastric mucosa and is strongly associated with gastrointestinal ulcers, chronic gas-tritis, gastric cancer, and other diseases. Recent studies have found that Helicobacter pylori infec-tion is also associated with many skin diseases, including but not limited to rosacea, chronic urti-caria, recurrent aphthous ulcers, Schönlein-Henoch purpura, and immune thrombocytopenic pur-pura. This article provides a review of studies on Helicobacter pylori infection and skin disorders to assist in clinical decision making.