食管胃结合部癌血清肿瘤标志物的研究进展

Research Progress of Serum Tumor Markers in Esophagogastric Junction Cancer

食管胃结合部癌近年来发病率逐年上升,早期发现是诊治的关键,如何在人群中筛查出食管胃结合部癌高危患者是当前的研究重点。血清学检测是最易推广和最便捷的方法,对食管结合部癌的诊断和筛查有重要意义,因此不断探索血清肿瘤标志物用于早期诊断和预后监测食管胃结合部癌是必要的。本文就近几年新型与传统血清肿瘤标志物在食管胃结合部癌中的研究进展作一综述。

In recent years, the incidence rate of esophagogastric junction cancer has increased year by year. Early detection is the key to diagnosis and treatment. How to screen high-risk patients of esoph-agogastric junction cancer in the population is the current research focus. Serological detection is the easiest and most convenient method to promote and has important significance for the diagno-sis and screening of esophagogastric junction cancer. Therefore, it is necessary to continuously ex-plore serum tumor markers for early diagnosis and prognosis monitoring of esophagogastric junc-tion cancer. This article reviews the research progress of new and traditional serum tumor markers in esophagogastric junction cancer in recent years.