生物可吸收血管支架在冠心病患者中的应用研究进展

Progress in the Application of Bioabsorbable Vascular Stents in Patients with Coronary Heart Disease

生物可吸收血管支架(Bioresorbable vascular scaffold, BVS)是一种新型的支架装置,它提供结构支持和药物释放,以防止早期反冲或再狭窄,然后降解为无毒化合物。可以避免与金属药物洗脱支架(drug-eluting stents, DESs)相关的晚期并发症。虽然BVS在冠心病患者中应用的优势性已被公认。然而,有研究表明使用BVS时,支架内血栓的发生率也较高,引起了临床广泛关注。因此,为了说明BVS的安全性和有效性,本研究采用文献综述的方法,对国内外生物可吸收血管支架在冠心病患者中的应用研究进展进行综述,以期为临床冠心病缓则支架的选择和相关研究提供借鉴。

Bioresorbable vascular scaffold (BVS) is a novel scaffold device that provides structural support and drug release to prevent early recoil or restenosis and then degrades into non-toxic compounds. Late complications associated with metal drug-eluting stents (DESs) can be avoided. Although BVS has been recognized for their superiority in patients with coronary heart disease, however, some stud-ies have shown that the incidence of stent thrombosis is also high when using BVS, which has aroused widespread clinical concern. Therefore, in order to illustrate the safety and effectiveness of BVS, this study adopts the method of literature review to review the research progress in the appli-cation of bioabsorbable vascular stents in patients with coronary heart disease at home and abroad, in order to provide references for the selection of stents in patients with chronic coronary heart disease and related studies.