口腔菌群与消化道肿瘤关系的研究进展

Advances in Research on the Relationship between Oral Flora and Gastrointestinal Tumours

口腔是人体内微生物菌群最丰富、最多样化的部位之一,仅次于胃肠道,由超过770种细菌组成。越来越多的证据表明,口腔内的细菌可以通过血行途径和肠道途径转移到胃肠道。口腔菌群向肠道的传播可能会加剧各种消化道肿瘤的进程。本文就口腔菌群与食管癌、胃癌、结直肠癌、胰腺癌等消化系统肿瘤关系展开综述,为后续的相关研究提供一定的参考。

The oral cavity is one of the richest and most diverse parts of the body in terms of microflora, second only to the gastrointestinal tract, and is composed of over 770 species of bacteria. There is growing evidence that bacteria from the oral cavity can be transferred to the gastrointestinal tract via the bloodstream and intestinal routes. The spread of oral flora to the gut may exacerbate the progres-sion of various gastrointestinal tumours. This paper reviews the relationship between oral flora and gastrointestinal tumours such as oesophageal, gastric, colorectal and pancreatic cancers, and pro-vides a reference for subsequent studies.