老年慢阻肺合并肌少症的相关研究进展

Research Progress of Chronic Obstructive Pulmonary Disease Complicated with Sarcopenia in the Elderly

慢性阻塞性肺病(COPD)是一种复杂、异质和多组分的疾病,除肺功能异常外,还常并发其他器官疾病,在COPD的多种并发症中,肌肉减少症是常见疾病之一,肌肉减少症是一种以肌肉质量、力量和健康减少为特征的综合征,其可以影响患者的死亡率和住院率。近年来,引起COPD患者肌肉功能障碍的新机制、预测其发生的生物标志物、相关危险因素及治疗被广泛研究,本文就老年COPD合并肌肉减少症的相关研究进展进行综述。

Chronic obstructive pulmonary disease (COPD) is a complex, heterogeneous and multicomponent disease, in addition to lung function abnormalities, also often complicated with other organ diseases;among the multiple complications of COPD, sarcopenia is one of the common diseases. Sarcopenia is a syndrome characterized by reduced muscle mass, strength and health. It can affect patient mor-tality and hospitalization rates. In recent years, the new mechanism of muscle dysfunction in pa-tients with COPD, biomarkers to predict its occurrence, related risk factors and treatment have been widely studied. This article reviews the research progress of COPD combined with sarcopenia in the elderly.