炎性因子和D-二聚体在主动脉夹层预后评估中的作用研究进展

Research Progress on the Role of Inflammatory Factors and D-Dimer in Prognosis Evaluation of Aortic Dissection

主动脉夹层是一种致命的心血管疾病,对人类的生命和健康构成严重威胁,手术治疗是目前唯一有效的治疗方法。然而,其术后易并发各种脏器感染,因此死亡率仍然居高不下。国内外最新文献报道监测血清炎性标志物水平与凝血功能有助于准确评估主动脉夹层患者的术后情况。本文拟回顾并综述炎性因子和D-二聚体在主动脉夹层预后评估中的作用研究进展,以期尽早评估患者术后预后情况,降低患者术后感染的风险,为临床感染防控提供相关依据。

Aortic dissection is a fatal cardiovascular disease, which poses a serious threat to human life and health. Surgical treatment is the only effective treatment at present. However, it is easy to be com-plicated with various organ infections after operation, so the mortality rate is still high. It is report-ed in the latest literature at home and abroad that monitoring the level of serum inflammatory markers and blood coagulation is helpful to accurately evaluate the postoperative condition of pa-tients with aortic dissection. This article reviews the research progress on the role of inflammatory factors and D-dimer in evaluating the prognosis of aortic dissection, in order to evaluate the post-operative prognosis of patients as soon as possible, reduce the risk of postoperative infection, and provide relevant basis for clinical infection prevention and control.