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外泌体在创面愈合中的应用

Application of Exosomes in Wound Healing
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摘要 外泌体是内体衍生的囊泡,在细胞间通讯中起关键作用,分泌于多种生物液体中,包括血清、唾液、尿液、腹水和脑脊液等。外泌体很小(直径30~150 nm),具有独特的胆质蛋白结构,它们可以在细胞之间携带和交换各种物质。在此,我们对各种来源的外泌体在不同创面恢复过程中的最新应用进行综述,并简要概述在各种生物医学领域的应用现状。 Exosomes are vesicles derived from endosomes, which play a key role in intercellular communica-tion and are secreted in various biological fluids, including serum, saliva, urine, ascites and cere-brospinal fluid. Exosomes are very small (30~150 nm in diameter) and have a unique bile protein structure, which can carry and exchange various substances between cells. Here, we review the lat-est application of exosomes from various sources in different wound healing processes, and briefly outline the application status in various biomedical fields.
出处 《临床医学进展》 2023年第6期9641-9647,共7页 Advances in Clinical Medicine
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