慢性阻塞性肺疾病急性加重期患者的血清指标与肺功能的关系

Relationship between Serum Indexes and Lung Function in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

慢性阻塞性肺疾病是以持续气流受限为特征的慢性炎症疾病。其病死率及死亡率较高,对经济发展及公共卫生都造成了很大的压力。肺功能检查是诊断慢性阻塞性肺疾病的重要工具,本文就炎症细胞、细胞因子、血清淀粉样蛋白(SAA)、降钙素原、超敏C反应蛋白及一些炎症比值指标在COPD中的作用及其分别与肺功能的关系做简要综述。帮助危重症患者不能配合完成肺功能检查及其他不抗拒原因造成肺功能低质量结果提供一定的证据支持。

Chronic obstructive pulmonary disease is a chronic inflammatory disease characterized by contin-uous airflow limitation. Its mortality rate is high, which has caused great pressure on economic de-velopment and public health. Pulmonary function examination is an important tool to diagnose chronic obstructive pulmonary disease. This article briefly reviews the roles of inflammatory cells, cytokines, serum amyloid, procalcitonin, high-sensitivity C-reactive protein and some inflammatory ratio indicators in COPD and their relationships with pulmonary function. To help critically ill pa-tients fail to cooperate with the completion of lung function examination and provide some evidence support for the low quality results of lung function caused by other irresistible reasons.