摘要
目的:探讨腓骨肌萎缩证(Charcot-Marie-Tooth, CMT)的临床表现、肌电图(electmyography, EMG)及遗传学的特征。方法:分析1例以首发症状为肢体麻木伴行走不稳的腓骨肌萎缩证患者的临床资料、辅助检查及治疗经过,结合相关文献后进行总结分析。结果:患者以四肢麻木,呈针刺样,行走活动后加重,休息后可缓解,晨轻暮重,持笔写字及执筷夹物欠佳为临床表现,经中西医结合治疗和康复训练治疗后,症状改善。结论:CMT是运动感觉的神经系统疾病,临床发病率低,临床医生对CMT认识不足,应详细询问病史、家族史及基因检测,综合考虑临床资料,从而降低误诊。
Objective: To explore the clinical manifestations, electromyography and genetic characteristics of charcot-marie-tooth syndrome. Methods: The clinical data, auxiliary examination and treatment of a case of charcot-marie-tooth syndrome with limb numbness and walking instability as the first symptom were retrospectively analyzed, and the relevant literature was combined to make a sum-mary analysis. Results: The patient’s limbs were numb, like acupuncture, aggravated after walking and could be relieved after rest, light in the morning and heavy in the evening, poor holding of pen and writing and chopsticks. The symptoms were improved after the treatment of integrated Chi-nese and Western medicine and rehabilitation training. Conclusion: CMT is a kinesthesia neurolog-ical disease with a low clinical incidence and insufficient knowledge of CMT by clinicians. Therefore, detailed medical history and comprehensive consideration of clinical data should be made to re-duce misdiagnosis.
出处
《临床医学进展》
2023年第7期11768-11774,共7页
Advances in Clinical Medicine
