摘要
2016年世界卫生组织提出2030年消除病毒性肝炎作为重大公共卫生危害的目标,并提出死亡率下降65%的明确目标。然而,经NAs类药物长期治疗后仍出现LLV的情况,并严重影响其预后如:促进肝纤维化进展、加重肝硬化和肝癌的发生。本文总结LLV的定义及发生率,发生概况及选择,对LLV的存在对CHB患者的影响进行综述,以供临床医师参考。
In 2016, the World Health Organization set a target of eliminating hepatitis as a major public health hazard by 2030, with a clear goal of reducing mortality by 65 percent. However, LLV still occurs af-ter long-term treatment with NAS drugs, which can seriously affect the prognosis of patients, such as promoting the progression of liver fibrosis, aggravating the occurrence of liver cirrhosis and liver cancer. This article summarized the definition and incidence of LLV, the general situation of occur-rence and selection, and the influence of the existence of LLV on CHB patients, so as to provide ref-erence for clinicians.
出处
《临床医学进展》
2023年第8期13038-13044,共7页
Advances in Clinical Medicine
