围孕期重金属因素暴露与营养因素缺乏对先天性心脏病的影响

The Impact of Heavy Metal Exposure and Nu-tritional Deficiency in Pregnant Pregnancy on Fetal Congenital Heart Disease

随着时代水平的变化,现实压力及新一代的思想自由化越发普遍,这一现象导致全国出生人口率较前显著下滑。公众已将优生优育的态度逐步刻入时代DNA。由于环境及生活方式的因素,怀孕期间接触有毒重金属及各种微量元素缺乏或摄入不足对胎儿发育异常产生了深远的负面影响。本综述以先天性心脏病为例,检索暴露于环境因素和母孕期相关微量元素补充等内部环境因素两方面对先心病的影响及其可能机制的相关文献进行综述,为疾病的预防提供基础。

Along with the change of the age level, real pressure and thought liberalization of a new generation are increasingly common, which causes a significant drop in the national birth population rate. The public has gradually etched the attitude of eugenics into the DNA of The Times. Due to environ-mental and lifestyle factors, pregnancy exposure to toxic heavy metals and all kinds of trace ele-ment deficiency or inadequate intake have a profound negative impact on abnormal fetal develop-ment. This review takes congenital heart disease as an example, retrieves the related literature on the effects of environmental factors and micronutrient supplementation during pregnancy on con-genital heart disease and the possible mechanisms, to provide the foundation for the prevention of disease.