反射式共聚焦显微镜指导白癜风临床治疗范围

Reflectance Confocal Microscopy Guides the Scope of Clinical Treatment of Vitiligo

目的:研究反射式共聚焦显微镜在白癜风诊疗中的应用。方法:利用反射式共聚焦显微镜观察171位我院白癜风患者皮损图像特征,图像中噬黑素细胞及淋巴细胞浸润情况。结果:进展期白癜风皮损边界及皮损内外多可见炎症浸润,稳定期白癜风皮损边界及边界外炎症浸润较少,皮损内未见炎症浸润者较多。对有炎症浸润的皮损区域进行治疗,稳定期皮损内未见炎症浸润者采用围白斑治疗。结论:反射式共聚焦激光扫描显微镜在白癜风的治疗方面应用广泛,能观察白癜风炎症浸润情况并指导白癜风的治疗范围。

Objective: To study the application of reflectance confocal microscopy in the diagnosis and treat-ment of vitiligo. Methods: Reflectance confocal microscopy was used to observe the features of skin lesions and the infiltration of melanophages and lymphocytes in 171 patients with vitiligo in our hospital. Results: Inflammatory infiltration was more common in progressive vitiligo than in stable vitiligo. Inflammatory infiltration was more common in stable vitiligo than in progressive vitiligo. The lesions with inflammatory infiltration were treated, and those without inflammatory infiltra-tion in the stable lesions were treated with perileukoplakia. Conclusion: Reflectance confocal laser scanning microscopy is widely used in the treatment of vitiligo, which can observe the inflammatory infiltration of vitiligo and guide the treatment range of vitiligo.