药物治疗骨质疏松症的研究进展

Research Progress in Drug Treatment of Osteoporosis

目前,老龄化问题在我国已日渐加重,骨质疏松症是老年人最为频发的疾病之一,已经属于严重危害中老年人健康的世界性难题,引起更多学者的关注。骨质疏松症(Osteoporosis, OP)是由各种原因造成的全身性、代谢性骨质问题,以骨量、骨强度的下降,骨结构及脆性的破坏增加,骨折风险增高为其显著特点。患者常常表现为疼痛不适,往往持续多年遂来就诊。X-ray表现:骨透亮度增加、骨小梁变细、骨皮质变薄等。根据临床指南可见骨质疏松症分为原发性和继发性二大类,其中原发性按照年龄及多发因素可分为女性绝经后和老年性。该怎样防治骨质疏松症是当前医生及患者所面对的最现实问题。迄今为止,骨质疏松症已成为内分泌科、骨科的钻研方向之一。本文旨在各大网站中查找有关内容整理归纳治疗骨质疏松症的中西医常见药物,为日后进一步研究防治骨质疏松症提供新方向。

At present, the problem of aging has become increasingly aggravated in China, osteoporosis is one of the most frequent diseases of the elderly, and it has become a worldwide problem that seriously endangers the health of middle-aged and elderly people, attracting more scholars’ attention. Oste-oporosis (OP) is a systemic and metabolic bone problem caused by various causes, characterized by a decrease in bone mass and strength, increased destruction of bone structure and fragility, and an increased risk of fracture. Patients often present with pain and discomfort, often presenting for years. X-ray manifestations include: increased bone translucency, thinning of trabeculae, thinning of bone cortex, etc. According to clinical guidelines, osteoporosis can be divided into primary and secondary categories, of which primary can be divided into female postmenopausal and senile ac-cording to age and multiple factors. How to prevent osteoporosis is the most realistic problem facing doctors and patients at present. So far, osteoporosis has become one of the research directions of endocrinology and orthopedics. This article aims to find relevant contents on major websites to or-ganize and summarize common drugs in traditional Chinese and Western medicine for the treat-ment of osteoporosis, and provide a new direction for further research on the prevention and treatment of osteoporosis in the future.