宫颈冷刀锥切术(CKC)与环形电刀锥切术(LEEP)治疗宫颈上皮内瘤变疗效及对妊娠的影响

The Efficacy of Cold Knife Conization (CKC) and Loop Electrosurgical Excision Procedure (LEEP) in the Treatment of Cervical Intraepithelial Neoplasia and Their Impact on Pregnancy

子宫颈上皮内瘤变(CIN)是宫颈癌的早期病变,而这种病变的发生与人乳头瘤病毒(HPV)的感染有关。子宫颈锥形切除术是治疗子宫颈上皮内瘤变的重要手段,LEEP术和CKC术是其主要的手术方式;然而,LEEP刀和CKC两种手术方式对治疗子宫颈上皮内瘤变后的疗效、治愈率、复发率、并发症以及对妊娠结局的影响是否具有差异,目前尚无统一的定论。因此,本文将对两种宫颈锥切手术术后结局以及对妊娠的影响做相关综述。

Cervical intraepithelial neoplasia (CIN) is an early lesion of cervical cancer, which is related to hu-man papillomavirus (HPV) infection. Cervical conization is an important method for the treatment of cervical intraepithelial neoplasia, and LEEP and CKC are the main surgical methods. However, there is no unified conclusion as to whether there are differences between LEEP knife and CKC in the cu-rative effect, cure rate, recurrence rate, complications and pregnancy outcome after cervical in-traepithelial neoplasia. Therefore, this article will review the outcome of two kinds of cervical coni-zation and the effect on pregnancy.