椎–基底动脉扩张延长症的血管内诊治研究进展

Research Progress in Endovascular Diagnosis and Treatment of Vertebrobasilar Dolichoectasia

椎–基底动脉扩张延长症(vertebrobasilar dolichoectasia, VBD),是一种颅内血管变异性疾病,发病机制尚未完全明确,可能与遗传或先天性因素有关。其异常的血管会导致多种临床疾病,包括脑卒中、脑积水、颅神经受压等。VBD所致的颅神经受压综合征的发病率逐年提高,随着医学影像学及血流动力学的发展,更多的无创检查及更清晰的图像为临床及相关研究提供了更好的条件,加之其本身可能导致的脑卒中等疾病,严重威胁患者的生命健康。因此,就椎–基底动脉(vertebrobasilar artery, VBA)迂曲延长综合征引起的相应症状及其存在的风险,从流行病学、临床症状及血管内治疗进展等方面研究进展作一综述。

Vertebrobasilar dolichoectasia (VBD) is a clinically rare intracranial posterior circulatory vascular variant disorder whose pathogenesis is not fully understood and may be related to genetic or con-genital factors. Its abnormal blood vessels can lead to a variety of clinical diseases, including stroke, hydrocephalus, cranial nerve compression, etc. With the development of medical imaging and he-modynamics, more non-invasive examinations and clearer images are provided conditions for clin-ical and related research, due to stroke and other diseases that may lead by themselves, seriously threatening patients’ life and health. Therefore, the corresponding symptoms and risks caused by vertebrobasilar artery (VBA) dolichoectasia syndrome are reviewed from the aspects of epidemiol-ogy, clinical manifestations and treatment.