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定量磁敏感成像在中枢神经系统中的研究进展及临床应用

Research Progress and Clinical Application of Quantitative Magnetic Sensitivity Imaging in the Central Nervous System
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摘要 定量磁敏感成像(QSM)是一种基于组织磁化率特性的新的非侵入性磁共振技术,可以量化局部组织的磁化率差异。QSM在监测血氧饱和度、区分微出血及钙化、显示含铁血黄素沉积等方面具有很大的优势。目前QSM在铁代谢相关性疾病、神经退行性疾病、脑血管性疾病中已展开了大量应用及研究,其在大脑以外的应用因易受呼吸和心跳引起的运动伪影的干扰而具有挑战性,本文就QSM在中枢神经系统的最新的研究进展与临床应用进行综述。 Quantitative susceptibility mapping (QSM) is a new non-invasive magnetic resonance imaging tech-nique based on tissue magnetization characteristics. It allows for the quantification of local tissue susceptibility differences. QSM has significant advantages in monitoring blood oxygen saturation, distinguishing microbleeds and calcifications and displaying iron deposition. Currently, there has been a considerable amount of application and research on QSM in iron metabolism-related diseas-es, neurodegenerative diseases, and cerebrovascular diseases. However, its application outside of the brain is challenging due to motion artifacts caused by respiration and heartbeat interference. This article provides a comprehensive review of the latest applications and research progress of QSM in the central nervous system.
作者 方胜哲 丁爽
出处 《临床医学进展》 2023年第11期17043-17049,共7页 Advances in Clinical Medicine
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