血压对心血管疾病预后的影响

The Effect of Blood Pressure on the Prognosis of Cardiovascular Disease

心血管疾病(CVD)是全球发病率和死亡率的主要原因,已成为世界性的问题。据报道,在普通人群和原发性高血压患者中血压(BP)是CVD的重要危险因素。其发病人群以老年人为主,但近期研究发现CVD的发病人群越来越年轻化,众所周知,血压对于CVD患者预后独立于其他影响因素。为此,探讨合理的血压控制范围,从而有效地降低心血管事件的发生显得尤为重要。但是目前鉴于CVD患者的血压控制目标的不确定性,进一步探讨CVD患者的收缩压及舒张压控制目标以及脉压、血压变异性、对CVD的预后影响进行阐述。

Cardiovascular disease (CVD) is a major cause of morbidity and mortality worldwide and has be-come a worldwide problem. Blood pressure (BP) has been reported to be an important risk factor for CVD in the general population and in patients with essential hypertension. Its incidence is pre-dominantly in the elderly, but in recent years the incidence of CVD has a tendency to be younger. It is well known that blood pressure is independent of other influencing factors on the prognosis of CVD patients. For this reason, it is particularly important to explore a reasonable range of BP control and thus the prognosis of cardiovascular events. However, at present, in view of the uncertainty of blood pressure control targets in patients with CVD, further exploration of systolic and diastolic blood pressure control targets in patients with CVD, as well as pulse pressure, blood pressure varia-bility, and the prognostic impact on CVD are described.