老年肾功能不全患者冠脉病变特点的相关研究进展

Research Progress on the Characteristics of Coronary Artery Lesions in Elderly Patients with Renal Insufficiency

慢性肾脏病(CKD)是冠状动脉疾病(CAD)发生发展的重要危险因素,具有较高的死亡率。CKD患者冠脉病变严重而复杂,除了糖尿病和高血压等传统冠心病危险因素外,CKD患者还暴露出其他与尿毒症相关的非传统心血管疾病危险因素。老年人因身体机能减退,多合并潜在肾功能不全,患者的肾小球滤过率明显下降,会导致其病情复杂,而目前大部分研究为非老年患者,因此,本文旨在通过对老年CKD中冠脉病变特点的分析,对老年慢性肾功能不全患者冠脉粥样硬化特点做如下综述。

Chronic kidney disease (CKD) is an important risk factor for the occurrence and development of coronary artery disease (CAD) with high mortality. Coronary artery disease in patients with CKD is serious and complex. In addition to traditional coronary heart disease risk factors such as diabetes and hypertension, CKD patients are also exposed to other non-traditional cardiovascular disease risk factors related to uremia. The glomerular filtration rate of elderly patients is significantly de-creased due to physical dysfunction and potential renal insufficiency, which will lead to a complex condition. At present, most of the studies are non-elderly patients. Therefore, this paper aims to summarize the characteristics of coronary atherosclerosis in elderly patients with chronic renal in-sufficiency through the analysis of the characteristics of coronary artery lesions in elderly patients with CKD.