血小板相关指标在假体周围感染诊断中的研究进展

Advances in Platelet-Related Markers in the Diagnosis of Periprosthetic Joint Infection

假体周围感染(Periprosthetic Joint Infection, PJI)作为关节置换术后常见的并发症之一,早期的诊断可以极大改善病人生活质量及降低治疗负担。虽然PJI的诊断近年来得到不断的完善和发展,但目前仍是一个难题,它需要血清学、组织病理学、影像学等各方面检验、检查结果进行综合判断,需要较高的检查费用且经常是有创检查;近年来,越来越多学者认为血小板相关指标对于假体周围感染有一定的早期筛查、诊断价值,并且有许多文章报道了血小板相关指标对PJI有较高的敏感性与特异性,这种血液指标的检验既简便快捷,又有数字化的检验结果,有较高的准确性,可以将其作为早期诊断PJI的参考工具。

Periprosthetic Joint Infection (PJI) is a common complication that can occur after arthroplasty. Early diagnosis of PJI is crucial as it can significantly improve patients’ quality of life and reduce the bur-den of treatment. Although the diagnosis of periprosthetic joint infection (PJI) has improved in re-cent years, it remains a challenging problem. It requires a comprehensive assessment of serology, histopathology, imaging, and other test and examination results. This comprehensive approach of-ten incurs high examination costs and is invasive. In recent years, an increasing number of scholars have recognized the potential of platelet-related indexes in the early screening and diagnosis of PJI. Numerous articles have reported that platelet-related indexes exhibit high sensitivity and specific-ity for PJI. Moreover, the blood test for these indexes is simple, quick, and provides accurate digital results. Therefore, platelet-related indexes can serve as a valuable reference tool for the early di-agnosis of PJI.