卡瑞利珠单抗治疗晚期高级别间叶源性肺恶性肿瘤1例并文献复习

Camrelizumab in the Treatment of Advanced High-Grade Mesenchymal Lung Malignancies: A Case Report and Literature Review

目的:探讨晚期高级别间叶源性肺恶性肿瘤及相关疾病临床特点及诊治方法。方法:报道1例经穿刺活检病理提示高级别间叶源性肺恶性肿瘤患者临床资料,并复习相关文献。结果:经1周期化疗联合免疫治疗后,效果显著,后续由于副反应严重,行卡瑞利珠单抗单药治疗2年余,目前处于临床完全缓解状态。结论:晚期间叶源性肺恶性肿瘤及相关组织类型可从免疫治疗中获益。

Objective: To investigate the clinical features, diagnosis and treatment of advanced high grade mesenchymal lung malignancies and related diseases. Methods: A retrospective analysis was per-formed for a patient with high-grade mesenchymal lung malignancy indicated by biopsy pathology and the relevant literature was reviewed. Results: After a cycle of chemotherapy combined with immunotherapy, the effect was significant. Due to serious side reactions, Camrelizumab was treated along for more than 2 years, and the patient was in complete response at present. Conclusion: Ad-vanced mesenchymal lung malignancies and related types can benefit from immunotherapy.