萎缩性骨不连的治疗研究进展

Research Progress in the Treatment of Atrophic Nonunion

目的:通过收集并整理现今萎缩性骨不连的治疗方法,提出相关研究的优势与不足,为未来研究方向和临床治疗提供思路。方法:检索SSCI、Pubmed、CNKI、VIP、万方数据库中从2000年1月1日开始,截止于2023年8月31日这一时间范围内,发表的有关萎缩性骨不连基础研究和临床研究的相关文献,对研究结果进行总结分析。结果:1) 萎缩性骨不连治疗仍以手术为主;2) 物理治疗、生物工程和中医治疗被认为有效,但存在一些不足;3) 随着近来3D打印等新技术的发展,萎缩性骨不连的治疗有了新的方向。结论:本研究对当前治疗萎缩性骨不连的方法统计较为全面,提出了当前研究的不足并指导了未来研究的方向。

Objective: To collect and sort out the current treatment methods of atrophic nonunion, put forward the advantages and disadvantages of related research, and provide ideas for future research direc-tions and clinical treatment. Methods: SSCI, Pubmed, CNKI, VIP, and Wanfang databases were searched for basic and clinical studies on atrophic nonunion published from January 1, 2000 to Au-gust 31, 2023, and the results were summarized and analyzed. Results: 1) The treatment of atrophic nonunion was still mainly surgery;2) Physiotherapy, bioengineering, and TCM treatments are considered effective, but have some shortcomings;3) With the recent development of new technologies such as 3D printing, the treatment of atrophic nonunion has a new direction. Conclu-sion: This study provides a comprehensive statistical analysis of the current methods for the treat-ment of atrophic nonunion, puts forward the shortcomings of the current research, and guides the direction of future research.