血糖控制水平与急性缺血性脑卒中预后关系的最新研究进展

Recent Research Advances on the Relationship between Glycemic Control Level and the Prognosis of Acute Ischemic Stroke

缺血性脑卒中是一种脑血管疾病,由脑血管病变引起脑组织缺血而产生。该疾病的发展过程中伴随大量细胞凋亡,导致高致残率和病死率。血糖控制在治疗和管理缺血性脑卒中中起着重要作用。保持血糖水平良好可以改善患者的预后,因为高血糖水平可能导致血管损伤、炎症反应和氧化应激等不良生理反应,进一步加剧脑组织缺血的损伤。调整血糖浓度,有助于降低各种副作用,推动脑部结构的重建与功能的提升,因此降低了死亡率和残障率,也改善了缺血性脑卒中病人的治疗效果。本文综述了近年来关于血糖控制水平对糖尿病合并缺血性脑卒中患者预后影响的相关研究。

Ischemic stroke is a cerebrovascular disease, caused by cerebral tissue ischemia caused by cere-brovascular disease. The development of the disease is accompanied by massive cell apoptosis, re-sulting in high disability and case fatality rates. Glycemic control plays an important role in the treatment and management of ischemic stroke. Maintaining a good blood glucose level can improve the prognosis of patients, because high blood glucose levels may lead to adverse physiological reac-tions such as vascular damage, inflammatory response and oxidative stress, further aggravating the damage of brain tissue ischemia. Adjusting blood glucose concentration can help reduce various side effects, and promote the reconstruction of brain structure and function, thus reducing the mortality and disability rate, and improving the treatment effect of ischemic stroke patients. This review summarizes recent studies on the impact of glycemic control levels on the prognosis of dia-betic patients with ischemic stroke.