维生素D治疗腹泻型肠易激综合征的研究进展

Vitamin D in the Treatment of Diarrhea Type Irritable Bowel Syndrome

随着社会日益发展、环境不断变化及心理压力的增大,肠易激综合征(Irritable bowel syndrome, IBS)在我国人群患病率呈逐渐升高趋势,因其发病机制较为复杂,目前尚无特效治疗方法;维生素D是一种常见的脂溶性维生素。研究发现,维生素D对缓解腹泻型肠易激综合征(IBS-D)的病情程度和改善患者生活质量具有一定的作用。本文对维生素D与IBS-D相关性的研究进展以及维生素D治疗IBS-D的疗效和作用机制作一综述,希望能为IBS-D的临床诊治提供新思路。

With the increasing development of society, changing environment, and increasing psychological pressure, the incidence of Irritable Bowel Syndrome (IBS) in the Chinese population is gradually increasing. Due to its complex pathogenesis, there is currently no specific treatment method. Vita-min D is a common fat-soluble vitamin. Research has found that vitamin D has a certain effect on al-leviating the severity of diarrhea induced irritable bowel syndrome (IBS-D) and improving the quality of life of patients. This article provides a review of the research progress on the correlation between vitamin D and IBS-D, as well as the efficacy and mechanism of vitamin D in the treatment of IBS-D. It is hoped to provide new ideas for the clinical diagnosis and treatment of IBS-D.