癫痫共患抑郁、焦虑相关机制的研究进展

Progress in the Study of Mechanisms Related to Depression and Anxiety in Epilepsy Co-Morbidity

近年来,癫痫共患病正在逐渐引起重视,其中癫痫共患抑郁、焦虑的发病率则高于其他精神疾病,且癫痫患者共患抑郁、焦虑将显著增加疾病负担、降低生活质量。目前研究发现,癫痫与抑郁、焦虑之间可能存在一些双向关系及共同的病理生理机制。本文将对此进行综述。

In recent years, epilepsy co-morbidities are gradually attracting attention, in which the prevalence of epilepsy co-morbid depression and anxiety is higher than that of other psychiatric disorders, and co-morbid depression and anxiety in epileptic patients will significantly increase the burden of dis-ease and reduce the quality of life. Current research has revealed that there may be some bidirec-tional relationships and common pathophysiological mechanisms between epilepsy and depression and anxiety. This article will review this issue.