肝细胞癌伴门静脉癌栓的综合治疗进展

Advances in the Combined Treatments of Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis

肝细胞癌(Hepatocellular carcinoma, HCC)是全世界最常见的消化道恶性肿瘤之一,其死亡率位居前列。肝癌(HCC)合并门静脉癌栓(Portal vein tumor thrombosis, PVTT)是影响晚期肝癌预后的重要因素,治疗策略目前在国际上还没有达成共识临床,临床证据表明采取单一治疗改善预后的效果并不理想,近年来围绕手术治疗,介入治疗,放疗和系统治疗等多学科联合治疗成为新的治疗趋势。本文就肝癌合并门静脉癌栓的多学科综合治疗最新治疗研究进展进行综述。

Hepatocellular carcinoma (HCC) is one of the most common gastrointestinal malignancies in the world with the high mortality rates. Hepatocellular carcinoma (HCC) combining with portal vein tumor thrombosis (PVTT) is an important factor affecting the prognosis of advanced hepatocellular carcinoma. Recently, there is still no international consensus on therapeutic strategies, and the clinical evidence shows that the effect of single therapy on improving prognosis is not ideal. So, the multidisciplinary combination of surgery, interventional therapy, radiotherapy and systematic therapy has become a new therapeutic trend. This article reviews the latest research progress of multidisciplinary comprehensive treatment of hepatocellular carcinoma with portal vein tumor thrombosis.