阻塞性睡眠呼吸暂停低通气综合征与血液学指标的研究进展

Research Progress on Obstructive Sleep Apnea Hypopnea Syndrome and Hematological Indicators

阻塞性睡眠呼吸暂停低通气综合征(OSAHS)是指因夜间睡眠过程中出现上呼吸道阻塞及狭窄导致的以血氧饱和度降低、伴或不伴有高碳酸血症为特征的睡眠呼吸障碍性疾病,其发病机制与神经、体液、内分泌因素密切相关。OSAHS病理生理机制复杂,可引起全身各系统及器官损害,并对外周循环血液学指标水平产生一定影响,本文主要对OSAHS参与影响的主要血液学指标进行综述。

Obstructive sleep apnea hypopnea syndrome (OSAHS) refers to a sleep respiratory disorder char-acterized by decreased blood oxygen saturation with or without hypercapnia due to upper respira-tory tract obstruction and stenosis during nighttime sleep. Its pathogenesis is closely related to neurological, humoral, and endocrine factors. The pathological and physiological mechanisms of OSAHS are complex, which can cause damage to various systems and organs throughout the body, and have a certain impact on the level of peripheral circulatory hematological indicators. This arti-cle mainly reviews the main hematological indicators involved in the impact of OSAHS.