孕早期血生化指标预测妊娠期糖尿病的研究进展

Research Progress on Blood Biochemical In-dexes in the First Trimester of Pregnancy in Predicting Gestational Diabetes

妊娠期糖尿病(GDM)的发病率高,且对母儿近期及远期健康均可造成不良影响。因此,早期发现GDM高危孕妇,尽早进行临床干预,对改善母婴预后至关重要。目前研究发现,多种血生化指标在孕早期与GDM的发生风险增加有关,包括糖类指标、血脂指标、脂肪因子、炎症因子等。本文对孕早期血生化指标预测GDM的研究进展进行综述,为建立合理的GDM孕早期预测模型提供依据。

Gestational diabetes mellitus (GDM) has a high incidence and can adversely affect the health of both mother and child in the near and long term. Therefore, early detection of pregnant women at high risk of GDM and early clinical intervention are crucial to improve maternal and infant prognosis. At present, studies have found that a variety of blood biochemical indicators are associated with an in-creased risk of GDM in the first trimester, including carbohydrate indexes, blood lipid indicators, adipokines, inflammatory factors, etc. This article reviews the research progress of blood biochemi-cal indicators in the first trimester of pregnancy in predicting GDM, so as to provide a basis for the establishment of a reasonable prediction model of GDM in the first trimester.