艾拉莫德治疗类风湿性关节炎的诊疗进展

Advances in the Diagnosis and Treatment of Rheumatoid Arthritis with Iguratimod

艾拉莫德(iguratimod, IGU)是一种改善风湿病情类药物,具有抑制炎症、减少骨破坏等作用,在类风湿性关节炎治疗中取得了良好的疗效。在临床试验中,IGU被证明优于安慰剂,其与其他抗风湿药物联合治疗使得疾病活跃度显著改善。在这篇综述中,我们总结了IGU的作用机制及其临床有效性和安全性的研究现状。

Iguratimod (IGU) is a kind of rheumatoid drug, which has the effect of inhibiting inflammation and reducing bone destruction, and has achieved good curative effect in the treatment of rheumatoid arthritis. In clinical trials, IGU was shown to be superior to placebo, and its combination with other anti-rheumatic drugs resulted in a significant improvement in disease activity. In this review, we summarize the current status of research on the mechanism of action of IGU and its clinical efficacy and safety.