心房颤动患者左心耳血栓相关研究进展

Research Progress on Left Atrial Appendage Thrombosis in Patients with Atrial Fibrillation

心房颤动是一种快速、不规则的房性心律,与多种严重并发症相关的多系统疾病,卒中作为其并发症之一,是目前卫生系统面临的重大挑战。左心耳由于其独特的结构与功能,具有较大的个体差异性,成为非瓣膜性房颤患者血栓形成主要部位。近年来随着左心耳检查技术的发展,对于规律使用抗凝药物仍发生血栓事件患者,左心耳封堵术是一种新方向,所以研究左心耳结构与功能对血栓防治具有重要意义。

Atrial fibrillation (AF) is a multi-system disease with rapid and irregular atrial rhythm, which is as-sociated with a variety of serious complications. Stroke, as one of its complications, is a major chal-lenge to the health system at present. Due to left atrial appendage (LAA) unique structure and function, it has great individual differences, which has become the main site of thrombosis in pa-tients with non-valvular AF. In recent years, with the development of LAA examination technology, LAA closure is a new direction for patients with thrombotic events despite regular use of anticoagu-lant drugs. Therefore, it is of great significance to study the structure and function of LAA for the prevention and treatment of thrombosis.