部分高危风险因素人群肠道准备的研究进展

Research Progress of Intestinal Preparation for Some High-Risk Factors

结肠镜检查是结直肠癌筛查的金标准,高质量的结肠镜检查需要充分的肠道准备。对于高风险人群,使用高容量聚乙二醇药物进行肠道准备,液体摄入量大,不良反应多,患者耐受性较差,目前约有18%~35%的患者肠道准备不充分。基于聚乙二醇肠道准备药物以及其他药物能减少液体摄入量,提高患者耐受性;同时,由于肠道准备人群具有高危风险因素,肠道准备前的饮食及其他药物使用的特异性有助于提高肠道准备成功率。本文旨在总结目前部分高危风险因素人群肠道准备效果,对其个性化肠道准备方案进行综述,给临床医生及结肠镜检查患者提供更好的选择。

Colonoscopy is the gold standard for colorectal cancer screening, and high-quality colonoscopy re-quires adequate bowel preparation. For the high-risk population, the use of high-volume polyeth-ylene glycol drugs for intestinal preparation has large fluid intake, many adverse reactions, and poor patient tolerance. At present, about 18%~35% of patients have inadequate intestinal prepa-ration. Polyethylene glycol based bowel preparation drugs and other drugs can reduce fluid intake and improve patient tolerance;At the same time, due to the high-risk factors of the intestinal prep-aration population, the specificity of diet and other drug use before intestinal preparation helps to improve the success rate of intestinal preparation. The purpose of this article is to summarize the effect of bowel preparation for some high-risk groups, and to review the bowel preparation methods and schemes, so as to provide better choices for clinicians and patients undergoing colonoscopy.