颅底脊索瘤放射治疗

Radiotherapy for Chordoma of Skull Base

颅底脊索瘤为少见肿瘤之一,生长缓慢,但具有高的复发倾向。手术是主要治疗手段,由于局部解剖结构影响,手术受到一定限制。通常采取手术后放疗或根治性放疗。随着放疗技术提高,立体定向放疗、调强治疗、质子治疗和碳离子治疗应用越来越广泛。不同放疗技术对生存影响和不良反应也存在差异。本文对颅底脊索瘤放疗的现状进行了综述。

Chordoma of skull base is one of the rare tumors with slow growth but high recurrence tendency. Surgery is the main method of treatment. Due to the influence of local anatomical structure, surgery is limited, usually taking postoperative radiotherapy or radical radiotherapy. With the improve-ment of radiotherapy technology, stereotactic radiotherapy, intensity modulated therapy, proton therapy and carbon ion radiotherapy are more and more widely used. Different radiotherapy tech-niques also have different effects on survival and adverse reactions. In this paper, the current status of radiotherapy for chordoma of skull base is reviewed.