利培酮治疗精神分裂症的临床效果及经济性研究进展

Research Progress on the Clinical Effect and Economy of Risperidone in the Treatment of Schizophrenia

精神分裂症是一种病理机制不明的慢性高致残性精神疾病,主要临床特征表现为思维、情感及行为紊乱和认知功能明显受损。现阶段药物治疗仍是临床上治疗精神分裂症的主流方法。第二代抗精神病药又称非典型抗精神病药,相对来说对患者认知功能影响较小,副作用较少,患者的依从性较好,是目前应用最广泛的抗精神病药物。本文就利培酮治疗精神分裂症的临床效果及经济性研究作一综述。

Schizophrenia is a chronic and highly disabling mental disease with unknown pathological mecha-nism. The main clinical characteristics are thinking, emotion and behavior disorders and obvious impairment of cognitive function. At present, drug therapy is still the mainstream method in clini-cal treatment of schizophrenia. Second-generation antipsychotics, also known as atypical antipsy-chotics, have relatively little impact on patients’ cognitive function, fewer side effects, and better patient compliance, making them the most widely used antipsychotics at present. This article re-views the clinical effect and economic study of risperidone in the treatment of schizophrenia.