青光眼睫状体炎综合征的病因及治疗进展

Etiology and Treatment Progress of Posner-Schlossman Syndrome

光眼睫状体炎综合征(Posner-Schlossman Syndrome, PSS)是1948年Posner和Schlossman首次报道。它是一种轻度非肉芽肿性前葡萄膜炎,易复发,单侧眼发病居多,伴眼压升高、角膜后沉着物、疼痛及视力下降,也可出现视神经损害。PSS发病多与病毒感染有关,其病因复杂。目前认为与巨细胞病毒、单纯疱疹病毒、炎症、免疫遗传因素及血管内皮功能等有关。抗病毒、抗炎及控制眼压为目前主要治疗方法,药物治疗预后不良也可选择手术治疗,而目前病因及治疗方法仍有争议。本文通过研究PSS的病因及治疗方法从而对PSS临床诊断及治疗提供参考。

Posner-Schlossman Syndrome was first reported by Posner and Schlossman in 1948. It is a mild non-granulomatous anterior uveitis prone to recurrence, unilateral eye disease, accompanied by increased intraocular pressure, posterior corneal accumulation, pain and vision loss, and can also appear optic nerve damage. The pathogeny of Posner-Schlossman Syndrome is more complicated than that of virus infection. Currently, it is thought to be related to cytomegalovirus, herpes simplex virus, inflammation, immune genetic factors and vascular endothelial function. At present, antiviral, anti-inflammatory and intraocular pressure control are the main treatment methods, and surgical treatment can also be selected for poor prognosis after drug treatment, but the cause and treat-ment method are still controversial. This paper studies the etiology and treatment of Posner- Schlossman syndrome to provide reference for clinical diagnosis and treatment of Posner- Schloss-man syndrome.