摘要
自噬是一种由自噬体介导的真核细胞代谢过程,在多种自身免疫性疾病中发挥作用。自噬异常可能导致自身免疫反应失调进而引发疾病。本文以免疫性血小板减少症、系统性红斑狼疮和类风湿关节炎等自身免疫性疾病为例,对自噬在自身免疫性疾病中的作用进行综述。
Autophagy is a eukaryotic cell metabolic process mediated by autophagosomes and plays a role in various autoimmune diseases. Autophagy abnormalities may lead to immune response dysregula-tion and consequently trigger disease development. This article provides an overview of the role of autophagy in autoimmune diseases, using examples such as immune thrombocytopenia, systemic lupus erythematosus, and rheumatoid arthritis.
出处
《临床医学进展》
2024年第3期1-7,共7页
Advances in Clinical Medicine
