原发性甲状旁腺功能亢进症对心血管系统影响的相关研究进展

Research Progress on the Effect of Primary Hyperparathyroidism on Cardiovascular System

原发性甲状旁腺功能亢进症是累及全身多个系统的内分泌疾病,通过甲状旁腺激素与钙离子的作用,原发性甲状旁腺功能亢进症除了对经典靶器官(骨骼及肾脏)的损害,对心血管疾病也有一定的损害,并可能导致发生心血管不良事件,且与死亡率也有相关性。本综述也探讨了关于PTX术后对心血管疾病的改善程度,但改善程度结果不一致。故为了今后原发性甲状旁腺功能亢进症导致的心血管疾病需要临床医生在工作中引起重视,现就原发性甲状旁腺功能亢进症的流行病学、发病机制及治疗方法进行综述,旨在为原发性甲状旁腺功能亢进症对心血管系统的影响提供理论依据。

Primary hyperparathyroidism is an endocrine disease involving many systems of the whole body. Through the action of parathyroid hormone and calcium ion, primary hyperparathyroidism not only damages the classical target organs (bones and kidneys), but also has certain damage to cardiovascular disease, and may lead to cardiovascular adverse events, and is also related to mortality. This review also discusses the degree of improvement of cardiovascular disease after PTX, but the results are not consistent. Therefore, in order to pay attention to the cardiovascular disease caused by primary hyperparathyroidism in the future, the epidemiology, pathogenesis and treatment of primary hyperparathyroidism are reviewed in order to provide theoretical basis for the effect of primary hyperparathyroidism on cardiovascular system.