抗氧化饮食对结直肠癌的预防及其机制

The Prevention and Mechanism of Antioxidant Diet on Colorectal Cancer

结直肠癌的发展是遗传和环境因素共同作用的结果,氧化应激是其重要病理机制之一。因此,饮食和生活方式的变化可能会改变结直肠癌的风险。而抗氧化饮食可以为机体提供抗氧化剂,如维生素A、维生素C和E、类胡萝卜素以及锌等微量营养元素。有大量数据表明,这些物质对肿瘤具有潜在的化学预防作用。本文将对它们在结直肠癌中的预防作用及其机制进行综述。

The development of colorectal cancer is the result of a combination of genetic and environmental factors, and oxidative stress is one of its important pathological mechanisms. Therefore, changes in diet and lifestyle may alter the risk of colorectal cancer. An antioxidant diet can provide the body with antioxidants, such as vitamin A, vitamin C and E, carotenoids and zinc. There is a wealth of data indicating that these substances have potential chemopreventive effects on tumors. This article will review their preventive effects and mechanisms in colorectal cancer.