结直肠癌治疗研究进展

Research Progress in the Treatment of Colorectal Cancer

根据国际癌症研究机构数据,结直肠癌是世界第三大常见癌症,也是导致癌症相关死亡的第二大原因,在全球范围内具有高发病率。本文就早期可切除结直肠癌、初始可切除性转移性结直肠癌的局部治疗及初始不可切除转移性结直肠癌的全身治疗完成综述。尽管结肠镜检查等早期筛查技术取得了进步,提高了患者的生存率,但或因此项为侵入性检查原因,仍有相当数量的患者贻误了诊治实际,在晚期才得到诊断,所以重点针对转移性结直肠癌患者的局部及全身治疗进行了阐述。

According to the International Agency for Research on Cancer reports, colorectal cancer is the third most prevalent form of cancer in the world and the second leading cause of cancer-related mortality, the global prevalence of this condition is significantly high. This article reviews the local treatment of early resectable colorectal cancer, initial resectable metastatic colorectal cancer, and systemic treatment of initial unresectable metastatic colorectal cancer. Although early screening techniques such as colonoscopy have made progress and improved the survival rate of patients, there are still a considerable number of patients who are delayed in diagnosis and treatment and are diagnosed at a late stage because of invasive examination. Therefore, the local and systemic treatment of patients with metastatic colorectal cancer is mainly discussed.