肝硬化门静脉血栓形成的研究进展

Research Progress on Portal Vein Thrombosis in Liver Cirrhosis

门静脉血栓形成是肝硬化的一种严重的并发症,可导致门脉高压和肝功能衰竭,进而引发严重后果,如食管胃底静脉曲张破裂出血、顽固性腹水和肝性脑病等,影响其预后和生活质量。过去几十年中,随着人们对门静脉血栓的逐渐重视,肝硬化门静脉血栓形成的研究也取得了一些进展,本文将从肝硬化门静脉血栓形成的发生机制、临床表现、相关因素、治疗及预后进行探讨,以期为临床预防和治疗提供科学依据。

Portal vein thrombosis is a serious complication of liver cirrhosis, which can lead to portal hypertension and liver failure, and then lead to serious consequences, such as esophageal and gastric variceal bleeding, refractory ascites and hepatic encephalopathy, which affect their prognosis and quality of life. In the past few decades, with the gradual attention to portal vein thrombosis, some progress has been made in the research of portal vein thrombosis in liver cirrhosis, and this article will discuss the pathogenesis, clinical manifestations and related factors of portal vein thrombosis in liver cirrhosis, in order to provide a scientific basis for clinical prevention and treatment.