新生儿坏死性小肠结肠炎临床进展

Clinical Progress of Neonatal Necrotizing Enterocolitis

新生儿坏死性小肠结肠炎是一种导致新生儿特别是早产儿死亡的严重胃肠道疾病,幸存者预后也不甚乐观。多年以来其发病机理仍有待进一步完善,新生儿坏死性小肠结肠炎的治疗也因此缺乏针对性措施,多以对症支持为主,面对严重的新生儿坏死性小肠结肠炎患儿,外科手术的干预结果也不尽如人意。因此寻找新生儿坏死性小肠结肠炎的相关危险因素,提前干预高危人群或是另一条出路。

Neonatal necrotizing enterocolitis is a serious gastrointestinal disease that leads to the death of newborns, especially premature infants. The prognosis of survivors is not very optimistic. For many years, the pathogenesis of neonatal necrotizing enterocolitis still needs to be further improved. Therefore, the treatment of neonatal necrotizing enterocolitis lacks targeted measures, and mostly focuses on symptomatic support. For the severe neonatal necrotizing enterocolitis, the results of surgical intervention are not satisfactory. Therefore, looking for the relevant risk factors of neonatal necrotizing enterocolitis, early intervention in high-risk groups may be another way.